A 64 year old man with altered sensorium who is unable to speak





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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment.


Date of admission: 28.12.22


A 64 year old male came to OPD with Chief complaints of 



Unable to speak since 8 days 


HOPI : The patient was apparently asymptomatic 13 days back then he developed cough which is insidious in onset and gradually progressive in nature. It is productive type which subsided on using medication.

He developed bowel and bladder incontinence along with loss of appetite since 13days. 

He developed hiccups and  loose stools 10 days back about 5 episodes per day last for 1 day where he was taken to a local doctor  which subsided on taking medication. 

And then since 7 days he stopped speaking and then was brought to our hospital 


Past history:

He is a known case of type 2 DM since 7years and is taking medication metformin and glimiperide since 4yrs.

No h/o HTN, asthma, epilepsy,CAD 


Personal history :

He used to work as a cattle rearer. Since the time he was diagnosed with diabetes he worked infrequently. From past 3 years he has stopped working as he is unable to walk without using stick. There is also drastic loss of weight since he became diabetic. 

Appetite - Lost 

Diet - Mixed

Bowel and bladder movements - incontinence 

(from past 2 days - constipation) 

Addictions - Occasional alcoholic ( during functions ) tobacco chewing daily since last 30 yrs 

No food / drug allergies 


Family history: 

His daughter had TB 7 yrs back and was treated 

His mother had TB 5 yrs back and was treated 


General examination : 

Patient is conscious, incoherent and uncooperative

He is moderately built and nourished 

Pallor : present 

Icterus : absent 

Cyanosis: absent 

Clubbing : absent 

Lymphadenopathy : absent 

Edema : absent




Vitals : 




Temp : 97.3 f 

Pulse : 100bpm

RR:20cpm

Bp:110/60 

Spo2: 98% 

Grbs: 193 mg/dl 


Systemic examination - 

CNS -

GCS :

E4,V1,M1



Sensory system - 

Pain , touch(fine & crude) , temp, vibration, joint position -  no response 

Motor system - 

                     Right                  Left

Tone -    UL   Hypo             Hypo

               LL   Hypo             Hypo

Power -  UL and LL no movement even with pain 

Reflexes - not elicited 

Brain stem reflexes - 

B/L corneal + , conjunctival + , pupillary + 

Cranial nerves - intact 

Finger nose in coordination - no 

Heel knee in coordination - no 

CVS -  S1,S2 heard, no murmurs ,no thrills 

Respiratory system  - decreased air entry on left side, crackles are heard, position of trachea - central 

Abdomen - soft,  non tender , no organomegaly









Bilateral flex ion deformity 


Investigations: 















usg


Provisional diagnosis: 


Altered Sensory secondary to meningoencephalitis,

Left sided pneumonia (Tb?)

Bilateral flex ion deformity since 2 years 


Treatment plan: 


03/01/2023


1) IVF 0.9 %NS IV @ 100 ml / hr 
2) Nebulization with duolin - 8th hrly , budecort - 12 th hrly
3) Inj .Thiamine 200 mg IV/BD in 100 ml NS 
4) Inj . Dexa 6 mg IV / TID 
5) ATT therapy PO/OD FDC:3 tab/ day
6) GRBS monitoring 6 th hrly
7) vitals monitoring 6 th hrly
8) Temp monitoring 4 th hrly
9) Inj H. Actrapid insulin SC TID acc to GRBS 
10)RT Feeds - 100 ml milk +3-4 scoops protein powder 4 th hrly , 50 ml H2O 2nd hrly
11 ) physiotherapy was done


04/01/2023


1) IVF 0.9%NS IV@ 100ml/hr 

2) inj.Thiamine 200mg IV/BD in 100ml NS 

3) inj Dexa 8mg iv/TID 

4)ATT therapy PO/OD 3tab/ day

5) monocef 2gm iv BD 

6)TAB ivabrad 5mg 

7)perinorm 20mg

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